Nocardia takedensis was first isolated in 2005, from soil in Japan. We report here two cases of lymphangitis in France (2012–2017) caused by N. takedensis both occurring after skin injury while gardening, which enabled its inoculation. The two patients were immunocompromised and successfully treated by an antimicrobial agent active on the isolated strain, trimethoprim-sulfamethoxazole and amoxicillin-clavulanic acid for patient one and patient two, respectively. Our study along with previous ones supports the idea of a newly recognized cutaneous opportunistic pathogen and reinforces the recommendation of using gloves during soil exposure for immunocompromised patients. Lastly, according to data found in the literature, we would recommend trimethoprim-sulfamethoxazole as an efficient empirical antibiotic therapy in case of cutaneous infection caused by N. takedensis.

中文翻译：

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诺卡氏菌：​​一种新发现的病原体，负责皮肤和软组织感染。

Takedensis诺卡氏菌最早于2005年从日本土壤中分离出来。我们在此报告了法国（2012-2017年）发生的两起由takedensis引起的淋巴管炎病例，这两例都是在园艺时皮肤受伤后发生的，因此可以对其进行接种。两名患者免疫功能低下，分别对一名患者和两名患者用对分离株具有活性的抗微生物药甲氧苄氨嘧啶-磺胺甲基异恶唑和阿莫西林-克拉维酸成功治疗。我们的研究与以前的研究一起支持了一种新认识的皮肤机会病原体的想法，并加强了对免疫受损患者在土壤中接触时使用手套的建议。最后，根据文献中的数据，