The rapid and accurate diagnosis of swine diseases is indispensable for reducing their negative impacts on the pork industry. Next-generation sequencing (NGS) is a promising diagnostic tool for swine diseases. To support the application of NGS in the diagnosis of swine disease, we established the Swine Pathogen Database (SPDB). The SPDB represents the first comprehensive and highly specialized database and analysis platform for swine pathogens. The current version features an online genome search tool, which now contains 26 148 genomes of swine, swine pathogens and phylogenetically related species. This database offers a comprehensive bioinformatics analysis pipeline for the identification of 4403 swine pathogens and their related species in clinical samples, based on targeted 16S rRNA gene sequencing and metagenomic NGS data. The SPDB provides a powerful and user-friendly service for veterinarians and researchers to support the applications of NGS in swine disease research.

中文翻译：

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SPDB：专门的数据库和基于Web的猪病原体分析平台

快速准确地诊断猪疾病对于减少其对猪肉行业的负面影响是必不可少的。下一代测序（NGS）是一种有前途的猪疾病诊断工具。为了支持NGS在猪疾病诊断中的应用，我们建立了猪病原体数据库（SPDB）。SPDB代表了第一个全面且高度专业化的猪病原体数据库和分析平台。当前版本具有在线基因组搜索工具，该工具现在包含猪，猪病原体和系统发育相关物种的26 148个基因组。该数据库基于目标16S rRNA基因测序和宏基因组NGS数据，为临床样品中的4403种猪病原体及其相关物种的鉴定提供了全面的生物信息学分析流程。