Abstract A mild and efficient base promoted, microwave assisted, green synthesis of 2-amino-2-ene-1,4-diones has been described by the decomposition of phenacyl azides followed by treatment with pyridinium salts of phenacyl bromides in aqueous media. A diverse range of substrates bearing electron-releasing and electron-withdrawing substituents were well tolerated and delivered corresponding 2-amino-2-ene-1,4-diones in good yields. Synthesized 2-amino-2-ene-1,4-diones have been further explored in the synthesis of various substituted 4-hydroxypyrrolidin-2-ones. Graphical Abstract

中文翻译：

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一种高效的微波加速苯甲酰叠氮化物和吡啶鎓苯甲酰盐的三组分反应：2-amino-2-ene-1,4-diones/pyrrolidin-2-ones 的简便环保方法

摘要 2-氨基-2-烯-1,4-二酮的温和有效的碱促进、微波辅助、绿色合成描述了通过苯甲酰叠氮化物的分解，然后用苯甲酰溴的吡啶鎓盐在水性介质中处理。各种带有电子释放和吸电子取代基的底物都具有良好的耐受性，并以良好的产率提供相应的 2-amino-2-ene-1,4-diones。合成的 2-amino-2-ene-1,4-diones 已在各种取代的 4-hydroxypyrrolidin-2-ones 的合成中得到进一步探索。图形概要