Abstract

Herein the microwave-assisted green synthesis of both silver (Ag) and copper (Cu) nanoparticles (NPs) by microwave irradiation have been successfully carried out using fresh ginger rhizome extract. Different analytical methods were used for the characterization of the nanoparticles. The size distribution of AgNPs was found from the range of 2.68 nm to 42.69 nm, whereas for CuNPs the size range was run from 11.32 nm to 33.70 nm in diameter. From the antibacterial assay, we found that both silver and copper nanoparticles demonstrated significant potentials against tested bacterial strains. Besides, in vitro cytotoxic effects of NPs were also tested on the L929 mouse fibroblast cell line through XTT cell viability assay which confirmed the non-toxic nature of AgNPs and CuNPs at all tested concentrations. Thus, the obtained biological properties, suggested the use of rhizome extract of Zingiber officinale mediated non-toxic AgNPs and CuNPs in further biomedical and clinical applications.

抽象的

本文中，已经使用新鲜的姜根茎提取物成功地进行了微波辅助的银（Ag）和铜（Cu）纳米粒子（NPs）的微波辅助绿色合成。使用不同的分析方法表征纳米颗粒。发现AgNPs的尺寸分布在2.68nm至42.69nm的范围内，而对于CuNPs，直径的尺寸范围在11.32nm至33.70nm之间。从抗菌分析中，我们发现银和铜纳米颗粒均显示出对测试细菌菌株的显着潜力。此外，体外还通过XTT细胞活力测定法在L929小鼠成纤维细胞系上测试了NPs的细胞毒性作用，该试验证实了在所有测试浓度下AgNPs和CuNPs的无毒性质。因此，获得的生物学特性表明，姜黄根茎提取物介导的无毒AgNPs和CuNPs在进一步的生物医学和临床应用中的用途。