Flexible pressure sensors have attracted great interest due to their application potential in healthcare monitoring, electronic-skin and human-machine interfaces. To satisfy the requirements from practical applications, the sensors with high sensitivity, broad linearity range and low detection limit are urgently desired. Here, flexible pressure sensors with the negative replica (N-Sensor) and the positive one (P-Sensor) of the irregular surface microstructures are systemically investigated to achieve high performances. As revealed by the in situ observation method, the positive replica which mainly contained convex microstructures exhibits smaller initial contact area and could be compressed more easily than the negative one with porous surface. Therefore, the performances of the P-Sensor including sensitivity, linearity range and detection limit are greatly improved. The P-Sensor exhibits high sensitivity of 163.4 kPa⁻¹ over a broad linearity range of 0–140 kPa, low detection limit of 1.3 Pa, fast response time (<10 ms) and good stability (>8000 cycles), which is one of the best results for flexible pressure sensors. Attributed to these excellent performances, the P-Sensor well performs in the measurements of human pulse, tactility and plantar pressure, showing great application potentials in human daily life.

柔性压力传感器由于其在医疗保健监控，电子皮肤和人机界面中的应用潜力而引起了极大的兴趣。为了满足实际应用的需求，迫切需要具有高灵敏度，宽线性范围和低检测限的传感器。在此，系统地研究了具有不规则表面微观结构的负副本（N传感器）和正副本（P传感器）的柔性压力传感器，以实现高性能。如原位观察方法所揭示的，主要包含凸微结构的正复制品显示出较小的初始接触面积，并且比具有多孔表面的负复制品更容易被压缩。因此，P传感器的性能包括灵敏度，线性范围和检测极限大大提高。P传感器具有163.4 kPa的高灵敏度在0-140 kPa的宽线性范围内，^-1的低检测极限（1.3 Pa），快速的响应时间（<10 ms）和良好的稳定性（> 8000次循环）下为^-1，这是柔性压力传感器的最佳结果之一。归因于这些出色的性能，P传感器在人体脉搏，触觉和足底压力的测量中表现出色，在人类日常生活中显示出巨大的应用潜力。