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Electrophile-Induced Reactions of Cross-Conjugated Enynones in the Synthesis of Heterocycles
Chemistry of Heterocyclic Compounds ( IF 1.5 ) Pub Date : 2020-08-20 , DOI: 10.1007/s10593-020-02739-9
Alena S. Pankova

Being compounds with multiple electrophilic centers, cross-conjugated enynones can be involved in various transformations upon treatment with electrophiles, in particular, Lewis and Brønsted acids, providing a convenient access to acyclic and cyclic compounds. This review covers literature data on electrophile-assisted reactions of substrates with cross-conjugated enynone scaffold toward the synthesis of heterocyclic compounds. The information is arranged according to the type of enynone motif, and chemical transformations of 2-(alkyn-1-yl)alk-2-en-1-ones and alk-1-en-4-yn-3-ones are discussed. The bibliography includes 52 sources.


中文翻译:

杂环合成中亲电诱导的共轭烯酮的反应

作为具有多个亲电中心的化合物,在使用亲电试剂(特别是路易斯酸和布朗斯台德酸)处理后,交叉共轭的烯酮可参与各种转化,从而方便地获得无环和环状化合物。这篇综述涵盖了文献的数据与亲电辅助底物与交叉共轭烯酮支架对杂环化合物合成的亲电反应。该信息是根据烯酮基序的类型排列的,并讨论了2-(alkyn-1-yl)alk-2-en-1-ones和alk-1-en-4-yn-3-ones的化学转化。参考书目包括52个资料来源。
更新日期:2020-08-20
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