Frontiers of Information Technology & Electronic Engineering ( IF 3 ) Pub Date : 2020-08-20 , DOI: 10.1631/fitee.1900211 Chen-lei Pang , Xu Liu , Wei Chen , Qing Yang
In this review, we introduce some chip-based waveguide biosensing and imaging techniques, which significantly reduce the complexity of the entire system. These techniques use a well-confined evanescent field to interact with the surrounding materials and achieve high sensitivity sensing and high signal-to-noise ratio (SNR) super-resolution imaging. The fabrication process of these chips is simple and compatible with conventional semiconductor fabrication methods, allowing high-yield production. Combined with recently developed chip-based light sources, these techniques offer the possibility of biosensing and super-resolution imaging based on integrated circuits.
中文翻译:
基于芯片的波导用于高灵敏度生物传感和超分辨率成像
在这篇综述中,我们介绍了一些基于芯片的波导生物传感和成像技术,这些技术显着降低了整个系统的复杂性。这些技术使用有限的渐逝场与周围的材料相互作用,并实现高灵敏度感测和高信噪比(SNR)超分辨率成像。这些芯片的制造过程很简单,并且与常规的半导体制造方法兼容,从而可以实现高产量的生产。结合最近开发的基于芯片的光源,这些技术提供了基于集成电路的生物传感和超分辨率成像的可能性。