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GFAP at 50.
ASN Neuro ( IF 4.7 ) Pub Date : 2020-08-18 , DOI: 10.1177/1759091420949680
Albee Messing 1, 2 , Michael Brenner 3
Affiliation  

Fifty years have passed since the discovery of glial fibrillary acidic protein (GFAP) by Lawrence Eng and colleagues. Now recognized as a member of the intermediate filament family of proteins, it has become a subject for study in fields as diverse as structural biology, cell biology, gene expression, basic neuroscience, clinical genetics and gene therapy. This review covers each of these areas, presenting an overview of current understanding and controversies regarding GFAP with the goal of stimulating continued study of this fascinating protein.



中文翻译:

GFAP 为 50。

自从 Lawrence Eng 及其同事发现胶质纤维酸性蛋白 (GFAP) 以来,已经过去了 50 年。现在被认为是蛋白质中间丝家族的一员,它已成为结构生物学、细胞生物学、基因表达、基础神经科学、临床遗传学和基因治疗等多种领域的研究课题。这篇综述涵盖了这些领域中的每一个,概述了当前对 GFAP 的理解和争议,目的是刺激对这种迷人蛋白质的持续研究。

更新日期:2020-08-19
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