Abstract The multifunctional Fe3O4/Au/Eu [1-(2-Naphthoyl)-3,3,3-trifluoroacetone]3 nanocomposite (NC) composed of luminescent europium(III) complex with 1-(2-naphthoyl)-3,3,3- trifluoroacetone (NTA) ligands (Eu(NTA)3), superparamagnetic Fe3O4 and plasmonic gold nanoparticles (FAEu(NTA)3) is developed for theranostic application. The FAEu(NTA)3 NC has been functionalized by 3-(mercaptopropyl)trimethoxysilane/3-(triethoxysilyl)-propylamine (MCPMS/TESPA) and conjugated with IgG antibody. This study was focused on luminescent properties and evaluation of the temperature dependent luminescence of FAEu(NTA)3 NC. The in vitro fluorescent imaging test of the prostate cancer PC3 cells incubated with FAEu(NTA)3 NC has been also presented.

中文翻译：

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基于多功能 Fe3O4/Au/Eu[1-(2-萘甲酰基)-3,3,3-三氟丙酮]3 纳米复合材料的纳米治疗学的发光特性

摘要 多功能 Fe3O4/Au/Eu [1-(2-Naphthoyl)-3,3,3-trifluoroacetone]3 纳米复合材料 (NC) 由发光的铕 (III) 与 1-(2-萘甲酰基)-3,3 ,3-三氟丙酮 (NTA) 配体 (Eu(NTA)3)、超顺磁性 Fe3O4 和等离激元金纳米粒子 (FAEu(NTA)3) 被开发用于治疗诊断应用。FAEu(NTA)3 NC 已被 3-(巯基丙基)三甲氧基硅烷/3-(三乙氧基甲硅烷基)-丙胺 (MCPMS/TESPA) 功能化并与 IgG 抗体偶联。本研究的重点是 FAEu(NTA)3 NC 的发光特性和温度依赖性发光的评估。还提出了与 FAEu(NTA)3 NC 孵育的前列腺癌 PC3 细胞的体外荧光成像测试。