Although numerous studies investigated the effect of UASMS2 polymorphism in leptin gene on cattle production, a consensus has not yet been reached. Therefore, we reviewed and meta-analyzed the effects of UASMS2 on cattle. We searched potentially relevant studies from seven databases (to December 25, 2019). Standard mean difference along with 95% confidence intervals was calculated to assess the strength of association through the random-effects model. Six published articles containing 1378 cattle samples were included in our meta-analysis. We found UASMS2 was not related to carcass weight, dressing percentage and loin muscle area in the recessive genetic model, but there was a significant association between UASMS2 and average daily weight gain, dry matter intake, body weight, marbling score, and backfat thickness. This meta-analysis indicated that UASMS2 was associated with growth and meat quality traits of cattle, implying that this SNP can be used reliably in beef cattle breeding. This study may provide valuable information on improving beef yield and quality in cattle production.

尽管许多研究调查了瘦素基因中UASMS2多态性对牛生产的影响，但尚未达成共识。因此，我们审查和荟萃分析了UASMS2对牛的影响。我们从七个数据库（到2019年12月25日）中搜索了可能相关的研究。计算标准平均差异以及95％的置信区间，以通过随机效应模型评估关联强度。我们的荟萃分析包括六篇包含1378头牛样品的已发表文章。在隐性遗传模型中，我们发现UASMS2与to体重，修整率和腰肌面积无关，但是UASMS2与平均日增重，干物质摄入量，体重，大理石花纹得分和背脂厚度之间存在显着关联。这项荟萃分析表明，UASMS2与牛的生长和肉质性状有关，这表明该SNP可可靠地用于肉牛育种。这项研究可能会提供有关提高牛的牛肉产量和质量的有价值的信息。