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Effective treatment and prevention of attempted suicide, anxiety, and aggressiveness with fluoxetine, despite proven use of androgenic anabolic steroids.
Drug Testing and Analysis ( IF 2.9 ) Pub Date : 2020-08-17 , DOI: 10.1002/dta.2912
Julio M X Amaral 1, 2 , Monica C Padilha 3 , Silvana V Chagas 4 , Julien S Baker 5 , Carrie Mullen 6 , Leonardo Vieira Neto 7 , Francisco R Aquino Neto 3 , Marcelo S Cruz 1
Affiliation  

The treatment of a man who attempted suicide after experiencing symptoms of anxiety and aggressiveness associated with the use of androgenic‐anabolic steroids (AAS) is described. This report includes 30 days of inpatient treatment and a 6‐month follow‐up. Regular use of fluoxetine apparently prevented the onset of anxiety, depression, aggressiveness, and suicide ideation, even with the concurrent use of AAS. The urinary concentration of androgens, metabolites of AAS, and fluoxetine were monitored through analysis of urinary samples by the Brazilian Laboratory of Doping Control. Our results are congruent with previous findings describing the risk of suicide prompted by AAS use as well as the efficacy of fluoxetine in the treatment of mood disorders associated with the use of anabolic steroids.

中文翻译:

尽管已证明使用雄激素合成代谢类固醇,但氟西汀仍可有效治疗和预防企图自杀、焦虑和攻击性行为。

描述了一名男子在经历与使用雄激素合成代谢类固醇 (AAS) 相关的焦虑和攻击性症状后企图自杀的治疗。该报告包括 30 天的住院治疗和 6 个月的随访。经常使用氟西汀显然可以预防焦虑、抑郁、攻击性和自杀意念的发生,即使同时使用 AAS。巴西兴奋剂控制实验室通过分析尿样监测雄激素、AAS 代谢物和氟西汀的尿浓度。我们的结果与之前的研究结果一致,这些研究结果描述了 AAS 使用引起的自杀风险以及氟西汀治疗与使用合成代谢类固醇相关的情绪障碍的功效。
更新日期:2020-08-17
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