Steroidogenic acute regulatory protein (STARD1) is regulated by phosphorylation and 14‐3‐3 protein binding. STARD1 is a key player in cholesterol transport in mitochondria, and its regulation is not fully understood. Tugaeva et al. provide novel insights on the site‐specific phosphorylation and subsequent 14‐3‐3‐dependent regulation of STARD1 function. These results may help us understand the mechanism behind the regulation of steroidogenesis.

中文翻译：

---

14-3-3蛋白在类固醇生成中的新作用。

类固醇形成的急性调节蛋白（STARD1）受磷酸化和14-3-3蛋白结合的调节。STARD1是线粒体胆固醇运输的关键参与者，其调控尚不完全清楚。Tugaeva等。提供有关位点特异性磷酸化以及随后的STARD1功能的14-3-3依赖性调节的新颖见解。这些结果可能有助于我们了解类固醇生成调控的机制。