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Interferon-λ at the Center of the Storm.
Immunity ( IF 32.4 ) Pub Date : 2020-08-18 , DOI: 10.1016/j.immuni.2020.07.024 Matthew R Hendricks 1 , Ram Savan 1
中文翻译:
风暴中心的干扰素-λ。
更新日期:2020-08-18
Immunity ( IF 32.4 ) Pub Date : 2020-08-18 , DOI: 10.1016/j.immuni.2020.07.024 Matthew R Hendricks 1 , Ram Savan 1
Affiliation
Type I and III interferons (IFNs) drive effective antiviral functions but differentially affect tissue homeostasis. Using mouse models of severe inflammation, Broggi et al. and Major et al. report in Science that type III IFNs disrupt epithelial cell proliferation and differentiation in the lung.
中文翻译:
风暴中心的干扰素-λ。
I型和III型干扰素(IFN)具有有效的抗病毒功能,但对组织动态平衡的影响不同。使用严重炎症的小鼠模型,Broggi等。和少校等。《科学》杂志报道说,III型干扰素破坏了肺上皮细胞的增殖和分化。