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Size Does Matter: Litter Size Strongly Determines Adult Metabolism in Rodents.
Cell Metabolism ( IF 29.0 ) Pub Date : 2020-08-18 , DOI: 10.1016/j.cmet.2020.07.014
Marcela Parra-Vargas 1 , Marta Ramon-Krauel 1 , Carles Lerin 1 , Josep C Jimenez-Chillaron 1
Affiliation  

In this essay, we highlight how litter size in rodents is a strong determinant of neonatal growth and long-term metabolic health. Based on these effects, we strongly advise that scientific articles that utilize rodent models for obesity and metabolic research should include information on the litter sizes in the study to increase the data transparency of such reports.



中文翻译:

大小很重要:窝的大小在很大程度上决定了啮齿动物的成年代谢。

在这篇文章中,我们强调了啮齿动物的产仔数是新生儿生长和长期代谢健康的重要决定因素。基于这些影响,我们强烈建议利用啮齿动物模型进行肥胖和代谢研究的科学文章应包括有关研究中产仔数的信息,以提高此类报告的数据透明度。

更新日期:2020-09-01
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