The glomerular array in the olfactory bulb of many vertebrates is segregated into molecularly and anatomically distinct clusters linked to different olfactory functions. In anurans, glomerular clustering is so far only described in Xenopus laevis. We traced olfactory projections to the bulb in tadpoles belonging to six distantly related anuran species in four families (Pipidae, Hylidae, Bufonidae, Dendrobatidae) and found that glomerular clustering is remarkably conserved. The general bauplan consists of four unequally sized glomerular clusters with minor inter-species variation. During metamorphosis, the olfactory system undergoes extensive remodeling. Tracings in metamorphotic and juvenile Dendrobates tinctorius and Xenopus tropicalis suggest a higher degree of variation in the glomerular organization after metamorphosis is complete. Our study highlights, that the anatomical organization of glomeruli in the main olfactory bulb (MOB) is highly conserved, despite an extensive ecomorphological diversification among anuran tadpoles, which suggests underlying developmental constraints.

中文翻译：

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在Anuran幼虫的主要嗅球中保护肾小球组织。

许多脊椎动物的嗅球中的肾小球阵列被分离成分子和解剖学上不同的簇，这些簇与不同的嗅觉功能相关。迄今为止，只有在非洲爪蟾中才描述了肾小球的聚集。我们追踪了嗅觉投射到t中的球茎，这些t属于四个科（Pipidae，Hylidae，Bufonidae，Dendrobatidae）的六个远缘相关的无色物种，并且发现肾小球的聚集非常明显。普通的鲍普兰由四个大小不等的肾小球簇组成，种间差异较小。在变态过程中，嗅觉系统经历了广泛的重塑。变态和幼小的石end和热带非洲爪蟾的示踪表明，变态完成后，肾小球组织的变化程度更高。