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Median nerve conduction studies in rabbits
BMC Neuroscience ( IF 2.4 ) Pub Date : 2020-08-17 , DOI: 10.1186/s12868-020-00584-2
Basak Mansiz-Kaplan 1 , Secil Pervane-Vural 1 , Koray Gursoy 2 , Baris Nacir 1
Affiliation  

Background When planning nerve conduction studies using animal models, the sciatic nerve is often used and the upper extremity nerves are not preferred due to the size of laboratory animals. This study aimed to present the method and mean values of median nerve conduction studies in laboratory rabbits. Fifty-five six-month-old male New Zealand white rabbits weighing 2 to 2.5 kg were included in nerve conduction studies performed under anesthesia. The compound muscle action potential amplitude and distal latency values were recorded for the median motor nerve with the electrodes placed on the flexor digitorum superficialis muscle and tendon. Results A total of 110 median nerves were evaluated. The mean amplitude of the median nerve was 30.6 ± 6.8, mV the median nerve distal latency was 1.3 ± 0.2 ms, and the mean intensity of stimulation inducing a response was 2.5 ± 1 mA. Conclusions The mean values obtained by the median motor nerve conduction method in this study can act as a guide for future nerve interventions undertaken in the upper extremities.

中文翻译:

兔正中神经传导研究

背景 在使用动物模型计划神经传导研究时,经常使用坐骨神经,并且由于实验动物的大小,上肢神经不是首选。本研究旨在介绍实验室兔正中神经传导研究的方法和平均值。55 只 6 个月大的雄性新西兰大白兔体重 2 至 2.5 公斤,被纳入在麻醉下进行的神经传导研究。将电极放置在趾浅屈肌和肌腱上,记录正中运动神经的复合肌肉动作电位幅度和远端潜伏期值。结果 共评估了 110 条正中神经。正中神经平均波幅为 30.6 ± 6.8,正中神经远端潜伏期 mV 为 1.3 ± 0.2 ms,诱导反应的平均刺激强度为 2.5 ± 1 mA。结论本研究中正中运动神经传导方法获得的平均值可以作为未来上肢神经干预的指导。
更新日期:2020-08-17
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