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MS, pregnancy and COVID-19
Multiple Sclerosis Journal ( IF 5.8 ) Pub Date : 2020-08-17 , DOI: 10.1177/1352458520949152
Charmaine Yam 1 , Vilija Jokubaitis 2 , Kerstin Hellwig 3 , Ruth Dobson 4
Affiliation  

Concerns regarding infection with the novel coronavirus SARS-CoV-2 leading to COVID-19 are particularly marked for pregnant women with autoimmune diseases such as multiple sclerosis (MS). There is currently a relative paucity of information to guide advice given to and the clinical management of these individuals. Much of the limited available data around COVID-19 and pregnancy derives from the obstetric literature, and as such, neurologists may not be familiar with the general principles underlying current advice. In this article, we discuss the impact of potential infection on the pregnant woman, the impact on her baby, the impact of the current pandemic on antenatal care, and the interaction between COVID-19, MS and pregnancy. This review provides a framework for neurologists to use to guide the individualised advice given to both pregnant women with MS, and those women with MS who are considering pregnancy. This includes evidence derived from previous novel coronavirus infections, and emerging evidence from the current pandemic.

中文翻译:

MS、怀孕和 COVID-19

对感染导致 COVID-19 的新型冠状病毒 SARS-CoV-2 的担忧在患有多发性硬化症 (MS) 等自身免疫性疾病的孕妇中尤为明显。目前相对缺乏信息来指导向这些人提供的建议和临床管理。许多关于 COVID-19 和怀孕的有限可用数据来自产科文献,因此,神经科医生可能不熟悉当前建议的一般原则。在本文中,我们讨论了潜在感染对孕妇的影响、对婴儿的影响、当前大流行对产前保健的影响,以及 COVID-19、MS 和怀孕之间的相互作用。本综述为神经科医生提供了一个框架,用于指导向 MS 孕妇和考虑怀孕的 MS 女性提供个性化建议。这包括来自先前新型冠状病毒感染的证据,以及来自当前大流行的新证据。
更新日期:2020-08-17
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