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Additively Manufactured Tantalum Implants for Repairing Bone Defects: A Systematic Review
Tissue Engineering, Part B: Reviews ( IF 6.4 ) Pub Date : 2021-04-16 , DOI: 10.1089/ten.teb.2020.0134
Hu Qian 1, 2 , Ting Lei 1 , Pengfei Lei 1 , Yihe Hu 1
Affiliation  

Tantalum has unique advantages as a biomaterial for repairing bone defects due to its outstanding bioactivity, excellent corrosion resistance, and mechanical properties. Ideal implants for bone repair should be of good biocompatibility and bioactivity, as well as ability to simulate the microstructure and mechanical environment of human bone tissues. Additive manufacturing can facilitate freedom of design for the macrostructure/microstructure of bone implants with controlled mechanical properties; thus, this method has great potential. Additively manufactured tantalum implants provide a novel alternative for bone repair and are gaining increasing attention. This systematic review aims to comprehensively summarize the subsistent evidence from physicochemical, cellular, animal, and clinical studies on additively manufactured tantalum implants in repairing bone defects, for the first time. This work may provide researchers an essential grasp on the advances of additively manufactured tantalum implants.

中文翻译:

用于修复骨缺损的增材制造钽植入物:系统评价

钽具有优异的生物活性、优异的耐腐蚀性和机械性能,作为一种修复骨缺损的生物材料具有独特的优势。理想的骨修复植入物应具有良好的生物相容性和生物活性,以及​​模拟人体骨组织微观结构和力学环境的能力。增材制造可以促进具有受控机械性能的骨植入物的宏观结构/微观结构的设计自由;因此,这种方法具有很大的潜力。增材制造的钽植入物为骨修复提供了一种新的替代方案,并且越来越受到关注。本系统综述旨在全面总结来自物理化学、细胞、动物、首次对增材制造的钽植入物修复骨缺损进行临床研究。这项工作可以为研究人员提供对增材制造钽植入物进展的基本掌握。
更新日期:2021-04-20
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