Exocrine pancreatic carcinoma is uncommon in the dog and the veterinary literature surrounding the disease is minimal. Twenty‐three cases of canine exocrine pancreatic carcinoma were reviewed in a retrospective manner to obtain information on clinical presentation, behaviour and survival associated with the disease. Presenting clinical signs were nonspecific and included anorexia, lethargy, vomiting and abdominal pain. The overall median survival time was only 1 day but was confounded by the large number of dogs that were euthanized shortly after diagnosis. Metastatic disease was detected in 78% of cases at the time of diagnosis, attesting to the aggressive nature of the disease. Neither lymph node metastasis, tumour size nor tumour location had an impact on overall survival. Only one patient was a previous diabetic who is contrary to reports of the disease in people and felines. This retrospective study reaffirms the need for early detection measures to optimize disease control. However, the benefits of therapy with surgery or radiation and adjuvant chemotherapy remain to be elucidated in dogs with exocrine pancreatic carcinoma.

中文翻译：

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23只犬胰腺外分泌癌的临床结果

外分泌胰腺癌在犬中并不常见，关于该疾病的兽医文献也很少。以回顾性方式审查了 23 例犬外分泌胰腺癌，以获得与该疾病相关的临床表现、行为和存活率的信息。临床症状是非特异性的，包括厌食、嗜睡、呕吐和腹痛。总体中位生存时间仅为 1 天，但被诊断后不久被安乐死的大量狗所混淆。78% 的病例在诊断时检测到转移性疾病，证明了该疾病的侵袭性。淋巴结转移、肿瘤大小和肿瘤位置均不影响总生存期。只有一名患者以前患有糖尿病，这与人类和猫科动物的疾病报告相反。这项回顾性研究重申了早期检测措施以优化疾病控制的必要性。然而，手术或放疗和辅助化疗对患有外分泌胰腺癌的犬的益处仍有待阐明。