Upconversion nanophosphors (UCNPs) are considered as an important synthesis arm within biomedical and energy sectors due to their unique optical characteristics, which can convert near‐infrared light into higher energy emissions. However, key challenges, cost, compatibility of the materials, etc. have to be taken into serious consideration to transform this in‐lab UCNPs technology into scale‐up production for wider commercial needs. This review highlights the fundamental concepts of synthetic approaches for UCNPs and recaps recent advances in terms of large‐scale production. A number of typical synthesis routes in both batch and continuous processes are reviewed, alongside their limitations and potential improvements when being considered for mass production. By discussing and exploiting the technical compacity for the potential synthetic trends, key challenges, and expectations of future synthesis methods for UCNPs are also outlined.

中文翻译：

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上转换纳米磷的可控制合成，以扩大规模生产

上转换纳米磷光体（UCNPs）由于其独特的光学特性而被认为是生物医学和能源领域的重要合成装置，可以将近红外光转换为更高的能量发射。但是，必须认真考虑关键挑战，成本，材料的兼容性等，才能将这种实验室中的UCNPs技术转变为按比例生产的规模，以满足更广泛的商业需求。这篇综述着重介绍了UCNP合成方法的基本概念，并回顾了大规模生产方面的最新进展。批处理和连续处理中的许多典型合成路线均经过审查，并考虑了它们的局限性和在考虑批量生产时可能的改进。通过讨论和利用潜在的综合趋势的技术适应性，