Three new azaphilones, sassafrin E (1), sassafrin F (2), and sassafrinamine A (3), were isolated from the filamentous fungus Aspergillus neoglaber. The structures of the compounds were determined by nuclear magnetic resonance spectroscopy, and were found to be novel analogues of two already known compound classes; sassafrins and berkchaetoazaphilones. Sassafrin E and F were both oxygen containing, while sassafrinamine A additionally contained a nitrogen atom, originating from an aminoethanol moiety, as well as extensive conjugation resulting in an intense purple colour of the pure compound. The structure of sassafrin E was further confirmed using deuterium exchange experiments coupled with high-resolution tandem mass spectrometry.

中文翻译：

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来自新曲霉的新氮杂苯甲酮。

从丝状真菌新曲霉中分离出三个新的azaphilones，sassafrin E（1），sassafrin F（2）和sassafrinamine A（3）。化合物的结构通过核磁共振波谱法测定，被发现是两种已知化合物类别的新型类似物。sassafrins和berkchaetoazaphilones。萨沙弗林E和F都含有氧，而萨沙弗林胺A还含有一个源自氨基乙醇部分的氮原子，以及广泛的共轭作用，导致纯化合物呈深紫色。使用氘交换实验和高分辨率串联质谱法进一步确定了萨沙弗林E的结构。