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Three New Benzazepine Alkaloids from
Heterocycles ( IF 0.6 ) Pub Date : 2020-07-03 , DOI: 10.3987/com-20-14296
Guang-Yu Yang , Min Zhou , Qiu-Fen Hu , Dian Luo , Na Lv , Ya-Ning Zhu , Lu Liu , Fan Wu , Dong Miao , Wei-Guang Wang , Qian Gao

Three new benzazepine alkaloids, cirrhobenzazepines A-C (1-3), together with four known alkaloids (4-7) were isolated from the whole plants of Thalictrum cirrhosum. Their structures were elucidated by spectroscopic methods, including extensive 1H, 13C, and 2D-NMR techniques. Compounds 1-7 were tested for their anti-rotavirus activity. The results revealed that compounds 1-7 exhibited potent anti-rotavirus activity with TI valves in the range of 11.9-18.2, respectively.

中文翻译:

三种新的苯并ze庚因生物碱

从整个拟南芥中分离出了三种新的苯并ze庚因生物碱,库仑苯并ze庚烷AC(1-3)和四种已知的生物碱(4-7)。通过包括广泛的1H,13C和2D-NMR技术在内的光谱方法阐明了它们的结构。测试化合物1-7的抗轮状病毒活性。结果表明,化合物1-7在TI瓣膜分别在11.9-18.2的范围内表现出强大的抗轮状病毒活性。
更新日期:2020-08-27
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