The genera Acremonium and Sarocladium comprise a high diversity of morphologically and genetically related fungi generally found in the environment, although a few species, mainly Sarocladium kiliense and Acremonium egyptiacum, can also be involved in many human infections. Clinical management of opportunistic infections caused by these fungi is very complex, since their correct identification is unreliable, and they generally show poor antifungal response. More than 300 clinical cases involving a broad range of Acremonium/Sarocladium infections have so far been published, and with this review we aim to compile and provide a detailed overview of the current knowledge on Acremonium/Sarocladium human infections in terms of presentation, diagnosis, treatments and prognoses. We also aim to summarise and discuss the data currently available on their antifungal susceptibility, emphasising the promising results obtained with voriconazole as well as their impact in terms of animal infections.

中文翻译：

---

Sarocladium 和 Acremonium 感染：一种古老的机会性真菌的新面孔

Acremonium 和 Sarocladium 属包括通常在环境中发现的形态和遗传相关的高度多样性真菌，尽管少数物种，主要是 Sarocladium kiliense 和 Acremonium egyptiacum，也可能与许多人类感染有关。由这些真菌引起的机会性感染的临床管理非常复杂，因为它们的正确识别是不可靠的，并且它们通常表现出较差的抗真菌反应。迄今为止，已经发表了 300 多例涉及广泛的枝顶芽孢菌/肉螟感染的临床病例，通过本次审查，我们的目标是汇编并详细概述目前关于枝顶芽孢杆菌/肉螈人类感染的表现、诊断、治疗和预后。