A cyclic lipodepsipeptide, verruculin, a rosigenin and an aposphaerin analogues, verruculinone and 7-O-methylaposphaerin C, together with six known compounds were isolated from the marine fungus Verruculina enalia BCC 22226. The structures of these compounds were elucidated by extensive spectroscopic analysis. The absolute configuration of verruculin was determined by Marfey's method, and the relative configuration of verruculinone was obtained by X-ray crystallography. Verruculin showed weak antituberculosis and antibacterial activities, while verruculinone displayed cytotoxicity against cancer cell (MCF-7 and NCI–H187) and Vero cell lines.

从海洋真菌Verruculina enalia BCC 22226中分离了环状脂肽肽，verruculin，rosigenin和a'phaerin类似物，verruculinone和7- O-甲基’ phaerin C以及六种已知化合物。通过广泛的光谱分析阐明了这些化合物的结构。Verruculin的绝对构型是通过Marfey法确定的，而Verruculinone的相对构型是通过X射线晶体学获得的。Verruculin显示出弱的抗结核和抗菌活性，而Verruculinone显示出对癌细胞（MCF-7和NCI-H187）和Vero细胞系的细胞毒性。