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Intraocular Chondrosarcoma in a Rabbit.
Journal of Comparative Pathology ( IF 0.8 ) Pub Date : 2020-08-15 , DOI: 10.1016/j.jcpa.2020.06.013
M Mikiewicz 1 , K Paździor-Czapula 1 , M Gesek 1 , P Dziubińska-Bartylak 2 , I Otrocka-Domagała 1
Affiliation  

Post-traumatic intraocular sarcomas are rarely reported in domestic animals and are most common in cats. An 8-year-old rabbit (Oryctolagus cuniculus) was referred to a veterinary clinic due to ocular discharge, uveitis and protein precipitate in the anterior chamber of the right eye. The eye was enucleated and histopathological examination revealed a poorly demarcated tumour within the ciliary body with invasion to adjacent eye structures. Neoplastic cells formed chaotic cartilage lacunae and were immunopositive for vimentin but immunonegative for pancytokeratin. On this basis, the neoplasm was diagnosed as a chondrosarcoma. To the best of our knowledge, this is the first report of intraocular chondrosarcoma in a rabbit. There was no history of previous ocular trauma but as there was serological evidence of Encephalitozoon cuniculi infection, inflammation could have been a predisposing factor to development of the neoplasm.



中文翻译:

兔眼内软骨肉瘤。

创伤后眼内肉瘤在家畜中很少报道,在猫中最常见。由于眼排出,葡萄膜炎和右眼前房中的蛋白质沉淀,将一只8岁的兔子(穴兔)转介到兽医诊所。摘除眼球,进行组织病理学检查,发现睫状体内的肿瘤界限不佳,并侵犯了相邻的眼部结构。肿瘤细胞形成混沌的软骨腔,波形蛋白免疫阳性,而全角蛋白免疫阴性。在此基础上,该肿瘤被诊断为软骨肉瘤。据我们所知,这是兔子眼内软骨肉瘤的首次报道。没有既往的眼外伤史,但有血清学证据cuniculi cuniculi感染,炎症可能是肿瘤发展的诱因。

更新日期:2020-08-15
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