Contact Lens & Anterior Eye ( IF 3.2 ) Pub Date : 2020-08-15 , DOI: 10.1016/j.clae.2020.08.001 Ananya Datta 1 , Mark D P Willcox 1 , Fiona Stapleton 1
Purpose
This study examined the rate and level of microbial contamination of silver and non-silver (control) barrel contact lens storage cases in vivo.
Methods
A prospective, single-centre, randomized, double blinded, crossover study was conducted to evaluate the efficacy of silver and control barrel cases used with an Oxipol™-based disinfecting solution over a two-month period. Lens cases were collected, and the frequency, type and level of microbial contamination evaluated using viable culture and standard identification methods. Questionnaires were used to assess the contact lens-related hygiene compliance of the participants.
Results
Forty eight daily contact lens wearers completed the study. Overall, 27 % of silver and 35 % control lens cases (P > 0.05) were contaminated, predominantly with Gram-positive bacteria. Only, 12 % of participants had good compliance, with 46 % having average compliance and 43 % poor compliance. Compliance score was not associated with level of microbial contamination. However, the use of hydrogel lenses in combination with silver cases compared to non-silver barrel cases resulted significantly greater numbers of bacteria colonising cases.
Conclusion
The present investigation demonstrated that the use of silver barrel cases does not reduce the overall rate and level of bacterial contamination, but that using hydrogel lenses in combination with silver cases resulted in higher numbers of bacteria isolated from cases.
中文翻译:
浸银桶形隐形眼镜储存盒的体内功效
目的
这项研究检查了体内银和非银(对照)桶形隐形眼镜储存盒的微生物污染率和水平。
方法
进行了一项前瞻性、单中心、随机、双盲、交叉研究,以评估在两个月内使用基于 Oxipol™ 的消毒溶液的银桶和对照桶的功效。收集镜片盒,并使用可行的培养和标准识别方法评估微生物污染的频率、类型和水平。问卷用于评估参与者与隐形眼镜相关的卫生依从性。
结果
四十八名每天佩戴隐形眼镜的人完成了这项研究。总体而言,27% 的银镜盒和 35% 的对照镜片盒 (P > 0.05) 受到污染,主要是革兰氏阳性菌。只有 12% 的参与者具有良好的依从性,46% 的参与者具有平均依从性,43% 的依从性较差。依从性评分与微生物污染水平无关。然而,与非银镜筒镜筒相比,将水凝胶镜片与银镜镜筒结合使用会导致细菌定植案例的数量显着增加。
结论
目前的调查表明,使用银镜筒并不能降低细菌污染的总体发生率和水平,但将水凝胶镜片与银镜结合使用会导致从镜筒中分离出更多的细菌。