LncRNA TPT1-AS1 Sponges miR-23a-5p in Glioblastoma to Promote Cancer Cell Proliferation,Cancer Biotherapy and Radiopharmaceuticals

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LncRNA TPT1-AS1 Sponges miR-23a-5p in Glioblastoma to Promote Cancer Cell Proliferation
Cancer Biotherapy and Radiopharmaceuticals ( IF 3.4 ) Pub Date : 2021-09-06 , DOI: 10.1089/cbr.2019.3484
Xianfeng Gao ₁ , Yang Cao ₂ , Jinglong Li ₃ , Chunyan Wang ₁ , Huaiqiang He ₄

Affiliation

Background: Long noncoding RNA (LncRNA) TPT1-AS1 is an oncogene in ovarian cancer and cervical cancer, while its role in glioblastoma (GBM) is unknown. The bioinformatics analysis in this study showed that miR-23a-5p may bind to TPT1-AS1. This study was performed to investigate the interactions between miR-23a-5p and TPT1-AS1 in GBM.

中文翻译：

LncRNA TPT1-AS1 在胶质母细胞瘤中海绵 miR-23a-5p 以促进癌细胞增殖

背景：长链非编码 RNA (LncRNA) TPT1-AS1 是卵巢癌和宫颈癌的致癌基因，但其在胶质母细胞瘤 (GBM) 中的作用尚不清楚。本研究中的生物信息学分析表明，miR-23a-5p 可能与 TPT1-AS1 结合。本研究旨在研究 GBM 中 miR-23a-5p 和 TPT1-AS1 之间的相互作用。

更新日期：2021-09-09

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