Abstract

Ultrasound assisted spray drying has been extensively used in the food and pharmaceutical industries for increasing the stability of variety of compounds involved in different applications, especially for drying sensitive compounds in the case of pharmaceutical industries. The use of ultrasonic spray drying has shown promising results in pharmaceutical sector though the application in food industries is still in the development stage possibly due to the absence of suitable designs, lower throughput values, and scale of operations. Considering these aspects, the current review focuses on the analysis of ultrasound-assisted spray drying for the food products and bioactive compounds so as to provide a better perception for the use in food processing industries. A detailed study into the diverse application of ultrasound in spray drying for encapsulation, microsphere generation, etc. in food industry and the enhancement into such applications using ultrasonic nozzle has been presented. Along with this, guidelines for the operating conditions involved in ultrasonic atomization for suitable applications with desired outputs and a detailed comparison with other nozzles have also been presented. Several advantages of ultrasonic spray drying over conventional method such as better size distribution, no nozzle clogging, lower velocity atomization, etc. have also been discussed. The low velocity spray generation using ultrasonic atomizers eliminates the requisite for large drying chambers thus, contributing to the compact designs. Overall, it has been clearly demonstrated that ultrasound offers lots of promise for improving the operations mainly with reduced processing times, enhanced production rates, and product quality.

摘要

超声波辅助喷雾干燥已广泛用于食品和制药行业，以提高不同应用中涉及的各种化合物的稳定性，尤其是在制药行业中干燥敏感化合物。尽管由于缺乏合适的设计、较低的吞吐量值和操作规模，超声波喷雾干燥在食品行业的应用仍处于发展阶段，但在制药行业中的使用已显示出可喜的成果。考虑到这些方面，当前的审查重点是对食品和生物活性化合物的超声辅助喷雾干燥的分析，以便为食品加工行业的使用提供更好的认识。详细研究了超声波在喷雾干燥中的各种应用，用于食品工业中的封装、微球生成等，以及使用超声波喷嘴对此类应用的增强。除此之外，还介绍了超声波雾化所涉及的操作条件指南，适用于具有所需输出的合适应用，并与其他喷嘴进行了详细比较。还讨论了超声波喷雾干燥相对于传统方法的几个优点，例如更好的尺寸分布、无喷嘴堵塞、较低的雾化速度等。使用超声波雾化器产生的低速喷雾消除了对大型干燥室的需求，从而有助于紧凑的设计。总体，