The crescent number of cases of candidiasis and the increase in the number of infections developed by non-albicans species and by multi-resistant strains has taken the attention of the scientific community, which has been searching for new therapeutic alternatives. Among the alternatives found the use of nanosystems for delivery of drugs already commercialized and new biomolecules have grown, in order to increase stability, solubility, optimize efficiency and reduce adverse effects. In view of the growing number of studies involving technological alternatives for the treatment of candidiasis, the present review came with the intention of gathering studies from the last two decades that used nanotechnology for the treatment of candidiasis, as well as analysing them critically and pointing out the future perspectives for their application with this purpose. Different studies were considered for the development of this review, addressing nanosystems such as metallic nanoparticles, mesoporous silica nanoparticles, polymeric nanoparticles, liposomes, nanoemulsion, microemulsion, solid lipid nanoparticle, nanostructured lipid carrier, lipidic nanocapsules and liquid crystals; and different clinical presentations of candidiasis. As a general overview, nanotechnology has proven to be an important ally for the treatment against the diversity of candidiasis found in the clinic, whether in increasing the effectiveness of commercialized drugs and reducing their adverse effects, as well as allowing exploring more effectively properties therapeutics of new biomolecules.

非白色念珠菌物种和多重耐药菌株引起的念珠菌病新月病例数量和感染数量的增加引起了科学界的关注，科学界一直在寻找新的治疗选择。在替代方案中，发现使用纳米系统来递送已经商业化的药物，并且已经出现了新的生物分子，以增加稳定性，溶解性，优化效率并减少不良影响。鉴于涉及用于治疗念珠菌病的技术替代方法的研究的数量在不断增加，因此，本综述的目的是收集过去二十年来使用纳米技术治疗念珠菌病的研究，并进行严格分析，并指出为此目的应用的未来前景。本综述的发展考虑了不同的研究，涉及纳米系统，例如金属纳米粒子，中孔二氧化硅纳米粒子，聚合物纳米粒子，脂质体，纳米乳液，微乳液，固体脂质纳米颗粒，纳米结构脂质载体，脂质纳米胶囊和液晶；以及念珠菌病的不同临床表现。总体而言，纳米技术已被证明是治疗临床上念珠菌多样性的重要盟友，无论是在提高商业化药物的有效性和减少其不良影响方面，还是使人们能够更有效地探索其治疗的特性。新的生物分子。本综述的发展考虑了不同的研究，涉及纳米系统，例如金属纳米粒子，中孔二氧化硅纳米粒子，聚合物纳米粒子，脂质体，纳米乳液，微乳液，固体脂质纳米颗粒，纳米结构脂质载体，脂质纳米胶囊和液晶；以及念珠菌病的不同临床表现。总体而言，纳米技术已被证明是治疗临床上念珠菌多样性的重要盟友，无论是在提高商业化药物的有效性和减少其不良影响方面，还是使人们能够更有效地探索其治疗的特性。新的生物分子。本综述的发展考虑了不同的研究，涉及纳米系统，例如金属纳米粒子，中孔二氧化硅纳米粒子，聚合物纳米粒子，脂质体，纳米乳液，微乳液，固体脂质纳米颗粒，纳米结构脂质载体，脂质纳米胶囊和液晶；以及念珠菌病的不同临床表现。总体而言，纳米技术已被证明是治疗临床上念珠菌多样性的重要盟友，无论是在提高商业化药物的有效性和减少其不良影响方面，还是使人们能够更有效地探索其治疗的特性。新的生物分子。聚合物纳米颗粒，脂质体，纳米乳剂，微乳剂，固体脂质纳米颗粒，纳米结构脂质载体，脂质纳米胶囊和液晶；以及念珠菌病的不同临床表现。总体而言，纳米技术已被证明是治疗临床上念珠菌多样性的重要盟友，无论是在提高商业化药物的有效性和减少其不良影响方面，还是使人们能够更有效地探索其治疗的特性。新的生物分子。聚合物纳米颗粒，脂质体，纳米乳剂，微乳剂，固体脂质纳米颗粒，纳米结构脂质载体，脂质纳米胶囊和液晶；以及念珠菌病的不同临床表现。总体而言，纳米技术已被证明是治疗临床上念珠菌多样性的重要盟友，无论是在提高商业化药物的有效性和减少其不良影响方面，还是使人们能够更有效地探索其治疗的特性。新的生物分子。