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Identification and characterization of miRNAs during early pregnancy in domestic sheep.
Animal Genetics ( IF 2.4 ) Pub Date : 2020-08-13 , DOI: 10.1111/age.12992
Kisun Pokharel 1 , Jaana Peippo 1 , Meng-Hua Li 2 , Juha Kantanen 1
Affiliation  

MicroRNA resources in sheep are limited compared with those in other domesticated mammalian species. By sequencing small RNAs of sheep corpus luteum and endometrium, we have generated the largest amount of miRNA‐seq data and compiled the most comprehensive list thus far of miRNAs (n = 599) in sheep. Additionally, we observed a highly conserved maternally imprinted cluster of miRNAs on chromosome 18 homologous to that found on chromosome 14 in human and several other eutherian mammals.

中文翻译:

在家中早期妊娠期间miRNA的鉴定和表征。

与其他驯养的哺乳动物相比,绵羊的MicroRNA资源有限。通过对绵羊黄体和子宫内膜的小RNA进行测序,我们获得了数量最多的miRNA-seq数据,并编制了迄今为止 绵羊中最完整的miRNA(n = 599)列表。此外,我们在人类和其他几只以太哺乳动物中观察到了高度保守的18号染色体miRNA母体印迹簇,该簇与14号染色体上的miRNA同源。
更新日期:2020-09-12
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