Cancer cell identity and plasticity are required in transition states, such as epithelial–mesenchymal transition (EMT) and mesenchymal–epithelial transition (MET), in primary tumor initiation, progression, and metastasis. The functional roles of EMT, MET, and the partial state (referred to as pEMT) may vary based on the type of tumor, the state of dissemination, and the degree of metastatic colonization. Herein, we review EMT, MET, pEMT, and plasticity in the context of tumor metastasis.

中文翻译：

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EMT、MET、可塑性和肿瘤转移。

在原发肿瘤的发生、进展和转移过程中，癌细胞的特性和可塑性是必需的，例如上皮-间充质转化 (EMT) 和间充质-上皮转化 (MET) 等过渡状态。EMT、MET 和部分状态（称为 pEMT）的功能作用可能因肿瘤类型、播散状态和转移性定植程度而异。在此，我们回顾了肿瘤转移背景下的 EMT、MET、pEMT 和可塑性。