Antimicrobial stewardship programs (ASPs) are collaborative efforts to optimize antimicrobial use in healthcare institutions through evidence-based quality improvement strategies. The general administration of pharmaceutical care in the Saudi ministry of health (MOH) is putting outstanding efforts in implementing antimicrobial stewardship in Saudi health care settings. Several surveys have been conducted globally and reported many types of antimicrobial stewardship strategies in health institutions and their effectiveness. This study aims to identify ASPs in Makkah region hospitals and their perceived level of success. We administered a regional survey to explore current progress and issues related to the implementation of ASPs in Makkah region hospitals at the pharmacy level (n = 25). Among responding hospitals, 19 (76%) hospitals, the most commonly reported ASP were as following: formulary restrictions (90%) for broad-spectrum antimicrobials and use of prospective feedback on antimicrobial prescribing (68%), use of clinical guidelines and pathways (100%), and use of automatic stop orders (68%) to limit inappropriate antimicrobial therapy. The study outcomes will also be of pivotal importance to devise policies and strategies for antimicrobial stewardship implementation in other non-MOH settings in the Makkah region. Based on our results, all reported institutions have at least one antimicrobial stewardship program in a process with a high success rate. A multidisciplinary ASP approach, active involvement of drug & therapeutic committee, formulary restrictions, and availability of education & training of pharmacists and physicians on ASP are the primary elements for perceived successful antimicrobial stewardship programs in the Makkah region hospitals.

抗菌素管理计划（ASP）是通过基于证据的质量改善策略来优化医疗机构中抗菌素使用的协作性努力。沙特卫生部（MOH）的药品管理总局在沙特医疗机构中实施抗菌素管理方面做出了出色的努力。全球已进行了几次调查，报告了卫生机构中许多类型的抗菌素管理策略及其有效性。这项研究旨在确定麦加地区医院的平均销售价格及其成功水平。我们进行了一项区域调查，以探讨药房级别（n = 25）在麦加地区医院中与ASP实施相关的当前进展和问题。在响应医院中，有19家（76％）医院，最常报告的ASP如下：广谱抗菌药物的处方限制（90％）和对抗菌药物处方的前瞻性反馈的使用（68％），临床指南和途径的使用（100％）以及自动停药命令的使用（68％）限制不适当的抗菌治疗。研究结果对于在麦加地区其他非卫生部环境中制定抗菌管理政策和策略也具有至关重要的意义。根据我们的结果，所有报告的机构在成功率很高的过程中至少都有一项抗菌素管理计划。多学科ASP方法，药物和治疗委员会的积极参与，处方限制以及教育和培训的可用性