Plants polysaccharides are an infinite stock of drug composites with varying pharmacological and biological activities. The present investigation aimed to examine the antibacterial, anti-scavenging and cytotoxic potential of garden cress (GC) polysaccharides. The antibacterial effects vs Escherichia coli and as well as Staphylococcus aureus of GC polysaccharides were examined by means of agar diffusion assay, minimum inhibitory concentration (MIC), outer and inner cell membrane permeability. Antioxidant potential of the GC polysaccharides were performed by free radical DPPH scavenging, superoxide anion scavenging, hydroxyl radical scavenging, reducing power potential assay, and hydrogen peroxide method. Cytotoxicity potential of GC polysaccharides were evaluated by MTT assay in human cervical (HeLa) and liver carcinoma (HepG2) cell lines. The findings showed that GC polysaccharides MIC were 1.06 and 0.56 mg mL⁻¹ against E. coli and S. aureus, respectively. Compared to the standard inhibitor, the GC polysaccharides showed essential inhibitor assays in a very dose dependent approach, and notable actions to scavenge reactive oxygen species (ROS) are also due to the large quantities of hydrophilic polyphenols. The IC₅₀ values of all tested parameters were measured against standard ascorbic acid antioxidant agent. The GC polysaccharides diminish the cell viability percentage of HeLa and HepG2 in a concentration dependent manner. GC polysaccharides at a dose of 500 µg ml⁻¹ exhibited higher anti-tumor activity in both HeLa (65.33 ± 3.75%) and HepG2 (60.33 ± 3.48%). The findings obtained in this study indicate that GC polysaccharides has antibacterial and has a possible source of natural antioxidant and also has cytotoxic effect on different carcinoma cell lines.

植物多糖是具有多种药理和生物活性的无限量的药物复合物。本研究旨在检查水芹（GC）多糖的抗菌，抗清除和细胞毒性潜力。对大肠杆菌和金黄色葡萄球菌的抗菌作用通过琼脂扩散测定，最小抑制浓度（MIC），细胞内外膜通透性检查GC多糖的含量。GC多糖的抗氧化电位通过自由基DPPH清除，超氧阴离子清除，羟基自由基清除，还原电势测定和过氧化氢方法进行。通过MTT分析评估了人参（HeLa）和肝癌（HepG2）细胞系中GC多糖的细胞毒性潜力。结果表明，GC多糖MIC为1.06和0.56 mg mL ^-1分别针对大肠杆菌和金黄色葡萄球菌。与标准抑制剂相比，GC多糖以非常依赖剂量的方法显示了重要的抑制剂检测方法，并且由于大量的亲水性多酚，清除活性氧（ROS）的显着作用也得到了体现。针对标准抗坏血酸抗氧化剂，测量了所有测试参数的IC ₅₀值。GC多糖以浓度依赖的方式降低HeLa和HepG2的细胞活力百分比。GC多糖，剂量为500 µg ml ^-1在HeLa（65.33±3.75％）和HepG2（60.33±3.48％）中均表现出更高的抗肿瘤活性。在这项研究中获得的发现表明，GC多糖具有抗菌作用，并且可能是天然抗氧化剂的来源，并且对不同的癌细胞系也具有细胞毒性作用。