Mebroqualone is an analogue of methaqualone, and there is a very little published information regarding the toxicity of this designer drug. We describe two cases with non-lethal levels of mebroqualone in blood collected at autopsy. Case 1 was an accidental death that involved a house fire, and the decedent was found to have a blood mebroqualone concentration of 10,228 ng/mL. Case 2 was a completed suicide by train, and the decedent was found to have a blood concentration of 115 ng/mL. To our knowledge, this is the first report in the scientific literature to compare two postmortem blood concentrations of mebroqualone. Mebroqualone was extracted from postmortem blood using a simple liquid–liquid extraction procedure and analyzed via gas chromatography–mass spectrometry.

中文翻译：

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涉及甲喹酮的两起死亡事件。

甲溴喹酮是甲喹酮的类似物，关于这种设计药物的毒性的公开信息很少。我们描述了两例尸检时采集的血液中甲溴喹酮非致死水平的病例。案例1是一起涉及房屋火灾的意外死亡，死者的血液中甲溴喹酮浓度为10,228 ng/mL。案例2为火车自杀，死者血浓度为115 ng/mL。据我们所知，这是科学文献中第一份比较两种死后血中甲喹酮浓度的报告。使用简单的液-液提取程序从死后血液中提取甲溴喹酮，并通过气相色谱-质谱法进行分析。