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A novel Betacoronavirus characterised in collared peccaries from the Rio de Janeiro Zoo (Brazil) killed by unknown disease.
Memórias do Instituto Oswaldo Cruz ( IF 2.8 ) Pub Date : 2020-08-10 , DOI: 10.1590/0074-02760200153
Mirela D'arc 1 , Matheus Calvano Cosentino 1 , Filipe Romero Rebello Moreira 1 , Liliane Tavares Faria Cavalcante 1 , Anderson Mendes Augusto 2 , Fernando Trocolli 2 , Daniel Guimarães Ubiali 3 , Carlos Eduardo Verona 2 , Marcelo Alves Soares 1 , André Felipe Santos 1
Affiliation  

In an enclosure with nine collared peccaries (Pecari tajacu) from the Rio de Janeiro city Zoo, Brazil, one specimen was found dead and two others developed prostration, apathy and dehydration, resulting on its death. Necropsy of two animals pointed to pulmonary and renal damage. Histological examination revealed vasculitis in spleen from both P. tajacu, suggesting a systemic viral infection. Lungs from one specimen showed fibrinoid vasculitis, alveolar damage with hyaline membrane, and interstitial lymphocytes infiltration. Virome analysis in anal wash samples from the latter two animals revealed a new type of Betacoronavirus, lineage A, provisionally named Ptajacu-CoV.

中文翻译:

一种新颖的β-冠状病毒,其特征是来自巴西里约热内卢动物园(Rio de Janeiro Zoo)的领兽,被未知疾病杀死。

在一个有九只来自巴西里约热内卢市动物园的领口野猫(Pecari tajacu)的围栏中,发现一个标本已死亡,另外两个标本垂死,冷漠和脱水,导致其死亡。两只动物的尸检指出肺和肾的损害。组织学检查发现两个塔氏疟原虫的脾脏都有血管炎,提示是全身性病毒感染。来自一个标本的肺显示纤维蛋白样血管炎,透明膜对肺泡的损害以及间质淋巴细胞的浸润。对后两只动物的肛门清洗样品进行的病毒学分析显示,一种新型的冠状病毒,谱系A,临时命名为Ptajacu-CoV。
更新日期:2020-08-20
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