Computational protein-protein docking is one of the most intensively studied topics in structural bioinformatics. The field has made substantial progress through over three decades of development. The development began with methods for rigid-body docking of two proteins, which have now been extended in different directions to cover the various macromolecular interactions observed in a cell. Here, we overview the recent developments of the variations of docking methods, including multiple protein docking, peptide-protein docking, and disordered protein docking methods.

中文翻译：

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不同类别的大分子相互作用的计算结构建模。

计算蛋白质-蛋白质对接是结构生物信息学中研究最深入的主题之一。经过三年多的发展，该领域取得了长足的进步。开发始于两种蛋白质的刚体对接方法，现在已经扩展到不同的方向，以涵盖在细胞中观察到的各种大分子相互作用。在这里，我们概述了对接方法的变化的最新发展，包括多蛋白质对接、肽-蛋白质对接和无序蛋白质对接方法。