This paper proposes two differential detection techniques for signal detection in mobile molecular communication (MMC) for targeted drug delivery (TDD) application. In MMC, a nano-transmitter and a nano-receiver are considered to be in Brownian motion in an extracellular fluid medium. Transmitter uses calcium molecules to communicate with the receiver. Detection is performed using concentration difference based detector (CDD) at the receiver which calculates the maximum absolute concentration difference of the received signal within the same bit interval to detect the bit. This improves the bit error rate (BER) performance in MMC. The performance is further enhanced using manchester coded transmission with differential detection (MCD). In MCD, Bit-1 is coded by the symbol [1 0] and Bit-0 is coded by the symbol [0 1] and the difference between peaks of signals received in consecutive bit duration is taken to detect the bit. Simulation results prove that the MCD technique is 3 dB less sensitive to inter symbol interference (ISI) than the CDD technique. The detection threshold is selected using maximum a posteriori probability (MAP) rule. The performance of these detectors is compared with other existing detection techniques. Results reveal that BER performance of the CDD and MCD better by at least 3 dB and 6 dB, respectively. The proposed CDD and MCD techniques perform better in different bit-sequence length, various initial distance and different bit duration than other existing techniques.

中文翻译：

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dMole：一种使用稳健差分检测技术的用于移动分子通信的新型收发器。

本文提出了两种用于靶向药物递送 (TDD) 应用的移动分子通信 (MMC) 信号检测的差分检测技术。在 MMC 中，纳米发射器和纳米接收器被认为在细胞外液介质中进行布朗运动。发射器使用钙分子与接收器通信。在接收器处使用基于浓度差的检测器 (CDD) 执行检测，该检测器计算相同位间隔内接收信号的最大绝对浓度差以检测位。这提高了 MMC 中的误码率 (BER) 性能。使用带有差分检测 (MCD) 的曼彻斯特编码传输进一步增强了性能。在 MCD 中，位 1 由符号 [1 0] 和 位 0由符号 [0 1] 编码，并采用在连续比特持续时间内接收到的信号峰值之间的差异来检测比特。仿真结果证明，MCD 技术对符号间干扰 (ISI) 的敏感度比 CDD 技术低 3 dB。使用最大后验概率 (MAP) 规则选择检测阈值。将这些检测器的性能与其他现有检测技术进行比较。结果表明，CDD 和 MCD 的 BER 性能分别提高了至少 3 dB 和 6 dB。与其他现有技术相比，所提出的 CDD 和 MCD 技术在不同的位序列长度、不同的初始距离和不同的位持续时间方面表现更好。