Trifunctional MAP‐based chiral phosphines were tested as new ligands in a Pd‐catalyzed asymmetric allylic alkylation, demonstrating fast and enantiodivergent catalysis. The palladium complexes of representative ligands by X‐ray analysis revealed a novel mode of P,N‐coordination of the ligand to the palladium center, which may contribute to switching the sense of the asymmetric induction via combined steric and tunable H‐bonding interactions between the metal complex and the substrates.

中文翻译：

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在钯催化的烯丙基烷基化反应中对映异构催化的多功能手性氨基膦。

基于三官能团MAP的手性膦在Pd催化的不对称烯丙基烷基化反应中作为新的配体进行了测试，证明了快速且对映异构的催化作用。X射线分析显示代表性配体的钯配合物揭示了一种新的P，N配位体与钯中心配位的模式，这可能通过在空间之间进行空间和可调H键结合的相互作用来切换不对称感应的方向。金属络合物和基材。