Purpose: This study examined whether a higher protein diet following strenuous exercise can alter markers of muscle damage and inflammation in older adults. Methods: Using a double-blind, independent group design, 10 males and eight females (age 57 ± 4 years; mass 72.3 ± 5.6 kg; height 1.7 ± 6.5 m) were supplied with a higher protein (2.50 g·kg⁻¹·day⁻¹) or moderate protein (1.25 g·kg⁻¹·day⁻¹) diet for 48 hr after 140 squats with 25% of their body mass. Maximal isometric voluntary contractions, muscle soreness, creatine kinase, Brief Assessment of Mood Adapted, and inflammatory markers were measured preexercise, and 24 hr and 48 hr postexercise. Results: The maximal isometric voluntary contractions decreased postexercise (p = .001, ${\mathrm{\eta }}_{\mathrm{p}}^2=.421$), but did not differ between groups (p = .822, ${\mathrm{\eta }}_{\mathrm{p}}^2=.012$). Muscle soreness peaked at 24 hr post in moderate protein (44 ± 30 mm) and 48 hr post in higher protein (70 ± 46 mm; p = .005; ${\mathrm{\eta }}_{\mathrm{p}}^2=.282$); however, no group differences were found (p = .585; ${\mathrm{\eta }}_{\mathrm{p}}^2=.083$). Monocytes and lymphocytes significantly decreased postexercise, and eosinophils increased 24 hr postexercise (p < 0.05), but neutrophils, creatine kinase, interleukin-6, C-reactive protein, monocyte chemotactic protein-1, and Brief Assessment of Mood Adapted were unchanged by exercise or the intervention (p > .05). Conclusion: In conclusion, 2.50 g·kg⁻¹·day⁻¹ of protein is not more effective than 1.25 g·kg⁻¹·day⁻¹ for attenuating indirect markers of muscle damage and inflammation following strenuous exercise in older adults.

目的：本研究探讨了剧烈运动后的高蛋白饮食是否可以改变老年人的肌肉损伤和炎症标志物。方法：采用双盲、独立分组设计，为 10 名男性和 8 名女性（年龄 57 ± 4 岁；体重 72.3 ± 5.6 kg；身高 1.7 ± 6.5 m）提供较高的蛋白质（2.50 g·kg ⁻¹ ·以体重的 25% 进行 140 次深蹲后，进行 48 小时的饮食（1.25 g·kg ^{-1 ·}天^-1 ）或中等蛋白质（1.25 g·kg -1 ·天在运动前以及运动后 24 小时和 48 小时测量最大等长随意收缩、肌肉酸痛、肌酸激酶、情绪适应的简要评估和炎症标记物。结果：运动后最大等长自主收缩减少（ p  = .001，${\mathrm{\eta }}_{\mathrm{p}}^2=.421$），但组间没有差异（p  = .822，${\mathrm{\eta }}_{\mathrm{p}}^2=.012$）。肌肉酸痛在中等蛋白质 (44 ± 30 mm) 后 24 小时达到峰值，在较高蛋白质 (70 ± 46 mm) 后 48 小时达到峰值；p  = .005；${\mathrm{\eta }}_{\mathrm{p}}^2=.282$）；然而，没有发现组间差异（p  = .585；${\mathrm{\eta }}_{\mathrm{p}}^2=.083$）。运动后单核细胞和淋巴细胞显着减少，运动后 24 小时嗜酸性粒细胞增加 ( p  < 0.05)，但中性粒细胞、肌酸激酶、白细胞介素 6、C 反应蛋白、单核细胞趋化蛋白 1 和情绪适应简要评估未因运动而改变或干预 ( p  > .05)。结论：总而言之，2.50 g·kg ^-1 ·天^-1蛋白质对于减轻老年人剧烈运动后肌肉损伤和炎症的间接标志物并不比 1.25 g·kg ^-1 ·天^{-1更有效。}