Asymmetric amplification is a phenomenon that is believed to play a key role in the emergence of homochirality in life. In asymmetric catalysis, theoretical and experimental models have been investigated to provide an understanding of how chiral amplification is possible, in particular based on non‐linear effects. Interestingly, it has been proposed a quarter century ago that chiral catalysts, when not enantiopure might even be more enantioselective than their enantiopure counterparts. We show here that such hyperpositive non‐linear effect in asymmetric catalysis is indeed possible. An in‐depth study into the underlying mechanism was carried out, and the scheme we derive differs from the previous proposed models.

中文翻译：

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醛催化非对称有机锌加成中的高正非线性效应的观察。

不对称扩增是一种现象，据信在生活中出现手性方面起着关键作用。在不对称催化中，已经研究了理论和实验模型，以了解如何进行手性扩增，尤其是基于非线性效应。有趣的是，四分之一世纪前有人提出，手性催化剂在不对映纯的情况下甚至可能比对映纯对映体具有更高的对映选择性。我们在这里表明，这种在非对称催化中的超正非线性效应确实是可能的。进行了对潜在机制的深入研究，我们得出的方案与先前提出的模型不同。