Compared to bacteria, fungi often exhibit a lower abundance and a higher temporal volatility in the intestinal microbiota. Analysis of fungi in the microbiota (mycobiota) faces technical limitations with tools that were originally developed for analyzing bacteria. Dysbiotic states of the intestinal mycobiota, often associated with disruption of the healthy bacterial microbiota, are characterized by overgrowth (domination) of specific fungal taxa and loss of diversity. Intestinal domination by Candida species has been shown to be a major source of Candida bloodstream infections. Fungal dysbiosis is also linked to the development and treatment response in non-fungal infections, for example Clostridioides difficile colitis and HIV. Further research is needed to define the contribution of intestinal mycobiota to human fungal and non-fungal infections.

中文翻译：

---

少数报告：全身感染中的肠道菌群。

与细菌相比，真菌在肠道微生物群中通常表现出较低的丰度和较高的时间波动性。微生物群（mycobiota）中的真菌分析面临着最初为分析细菌而开发的工具的技术限制。肠道菌群的失调状态，通常与健康细菌微生物群的破坏有关，其特征是特定真菌类群的过度生长（支配）和多样性的丧失。念珠菌属的肠道支配已被证明是念珠菌血流感染的主要来源。真菌生态失调也与非真菌感染的发展和治疗反应有关，例如艰难梭菌结肠炎和 HIV。需要进一步的研究来确定肠道菌群对人类真菌和非真菌感染的贡献。