PURPOSE Toxic stress has been identified as a key mechanism by which poverty impacts health and empirical evidence on the relationship between poverty and biological markers of toxic stress is accumulating. This study synthesizes the empirical evidence of the relationship between poverty and biomarkers of toxic stress. METHOD We conduct a systematic literature review using PRISMA guidelines to assess the relationship between poverty and toxic stress. A total of 56 articles are included in the review assessing 63 poverty and toxic stress relationships. RESULTS Seventeen of 30 reviewed relationships showed a statistically significant relationship between our measures of poverty and biomarker outcomes. Additionally, 12 of the remaining 13 studies demonstrated partially statistically significant relationship between our poverty measures and biomarker outcomes. CONCLUSION Findings demonstrate evidence of the relationship between poverty and toxic stress. Consistently, poverty was related to biological stress and neighborhood poverty was related to physical stress outcomes.

中文翻译：

---

对贫困与毒性应激生物标志物之间关联的系统评价

用途毒性应激已被认为是贫穷影响健康的关键机制，并且积累了关于贫穷与毒性应激生物学标记之间关系的经验证据。这项研究综合了贫困与毒性应激生物标志物之间关系的经验证据。方法我们使用PRISMA指南进行了系统的文献综述，以评估贫困与毒性应激之间的关系。该评价总共包括56条文章，评估了63种贫困与毒性压力之间的关系。结果30个被审查的关系中有17个表明我们的贫困程度与生物标志物结果之间存在统计学上的显着关系。另外，其余13项研究中的12项表明，我们的贫困衡量与生物标志物结果之间存在部分统计学上的显着关系。结论研究结果证明了贫困与毒性压力之间的关系。贫困总是与生物压力有关，邻里贫困与身体压力有关。