Infertility may be associated with severe psychological burden and many couples need mental support. We used dyadic approach to identify couples with disturbed psychological condition and we tested the WHO-5 Well-Being Index (WHO-5-WBI) questionnaire as a possible, rapid screening method. Extensive psychological assessment of infertile couples was carried out with Beck’s Depression Inventory, Spielberger State-Trait Anxiety Inventory, WHO-5-WBI, Symptom Check List-90 Revised Test, Fagerstrom Test for Nicotine Dependence, Alcohol Use Disorders Identification Test. Data of 128 patients (64 couples) were used in the statistical calculations. The Two-Step cluster analysis has revealed 2 groups, which could be separated supremely based on the level of experienced depression, anxiety and according to the general mental health. The WHO-5-WBI questionnaire showed consistent results while classifying couples into groups, which were formed. Our results indicate that infertility affects both spouses almost in the same extent in several psychological aspects. A cluster of couples with increased psychological burden could be clearly separated. The WHO-5-WBI questionnaire was a promising tool to screen reliably spouses based on their psychological state and identify couples that need psychological support during their fertility work-up and treatment.

中文翻译：

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使用二元法对不育夫妇进行聚类：WHO-5-WBI 作为评估心理状态的有希望的工具

不孕症可能与严重的心理负担有关，许多夫妇需要精神支持。我们使用二元法来识别心理状况不佳的夫妇，并测试了 WHO-5 幸福指数 (WHO-5-WBI) 问卷作为一种可能的快速筛查方法。使用贝克抑郁量表、斯皮尔伯格状态-特质焦虑量表、WHO-5-WBI、症状检查表-90 修订测试、Fagerstrom 尼古丁依赖测试、酒精使用障碍识别测试对不育夫妇进行了广泛的心理评估。128 名患者（64 对夫妇）的数据用于统计计算。两步聚类分析揭示了 2 组，可以根据经历的抑郁、焦虑程度和一般心理健康状况将其分开。WHO-5-WBI 问卷显示出一致的结果，同时将已形成的夫妻分组。我们的研究结果表明，不孕症在几个心理方面对配偶双方的影响几乎相同。一群心理负担增加的夫妇可以清楚地分开。WHO-5-WBI 问卷是一种很有前景的工具，可以根据配偶的心理状态对其进行可靠的筛查，并确定在生育检查和治疗期间需要心理支持的夫妇。