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Saliva-based PCR tests for SARS-CoV-2 detection.
Journal of Oral Science ( IF 1.9 ) Pub Date : 2020-06-23 , DOI: 10.2334/josnusd.20-0267
Yoshimasa Takeuchi 1, 2 , Mika Furuchi 1, 2 , Atsushi Kamimoto 1, 2 , Kazuya Honda 3 , Hideo Matsumura 4 , Ryutaro Kobayashi 5
Affiliation  

The outbreak of novel coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread worldwide. Nasopharyngeal swabs are widely used in polymerase chain reaction (PCR) test to detect SARS-CoV-2. However, the collection of nasopharyngeal swabs has a series of drawbacks concerning exposure of healthcare staff, difficulty in collection, and discomfort of patients. Therefore, an alternative noninvasive sample for diagnostic of emerging viral diseases is required. The usefulness of saliva screening tests is compared to conventional swab tests in this report. The results suggest that saliva could be a reliable sample for detecting SARS-CoV-2.



中文翻译:

用于SARS-CoV-2检测的基于唾液的PCR测试。

由严重急性呼吸系统综合症冠状病毒2(SARS-CoV-2)引起的新型冠状病毒病2019(COVID-19)的爆发已在全球范围内蔓延。鼻咽拭子广泛用于聚合酶链反应(PCR)测试中以检测SARS-CoV-2。然而,鼻咽拭子的收集具有与医护人员接触,收集困难和患者不适有关的一系列缺点。因此,需要用于诊断新兴病毒性疾病的替代性非侵入性样品。在本报告中将唾液筛查测试与常规拭子测试的有用性进行了比较。结果表明,唾液可能是检测SARS-CoV-2的可靠样品。

更新日期:2020-08-23
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