In this study, the wettability, cell viability, and roughness of an experimental dense bovine hydroxyapatite [Ca₁₀(PO₄)₆(OH)₂] ceramic block were evaluated so that, in the future, it could be used as a base material for dental implants. The results to commercial zirconia and a commercially pure titanium (Ti) alloy were compared. The surface roughness and contact angles were measured. An in vitro evaluation was conducted by means of tests in which pre-osteoblastic MC3T3-E1 cells were placed in indirect and direct contact with these materials. For cell viability, a 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay and crystal violet test were conducted. A qualitative analysis was conducted using variable pressure scanning electron microscopy (SEM). No statistically significant differences were observed in wettability and roughness tests among the groups. In both the MTT assay and crystal violet test, all groups demonstrated satisfactory results without cytotoxicity. SEM showed cell adhesion and cell proliferation results on the material surfaces after 24 h and 48 h. In conclusion, this dense Ca₁₀ (PO₄)₆(OH)₂ ceramic can be considered as a potential biocompatible material.

在这项研究中，评估了实验性致密的牛羟基磷灰石[Ca ₁₀（PO ₄）₆（OH）₂ ]陶瓷块的润湿性，细胞生存力和粗糙度，以便将来用作基础材料。用于牙种植体。比较了商用氧化锆和商用纯钛（Ti）合金的结果。测量表面粗糙度和接触角。一种在体外通过将成骨细胞前MC3T3-E1细胞与这些材料间接和直接接触的试验进行评估。对于细胞生存力，进行了3​​-（4,5-二甲基噻唑-2-基）-2,5-二苯基溴化四唑（MTT）测定法和结晶紫测试。使用可变压力扫描电子显微镜（SEM）进行定性分析。各组之间在润湿性和粗糙度测试中未观察到统计学上的显着差异。在MTT试验和结晶紫试验中，所有组均显示出令人满意的结果而没有细胞毒性。SEM显示在24小时和48小时后材料表面上的细胞粘附和细胞增殖结果。总之，这种致密的Ca ₁₀（PO ₄）₆（OH）₂陶瓷可以被认为是潜在的生物相容性材料。