Propolis is a sticky, resinous material gather from plants and is blended with wax and other constituents. It is reported to have anti-inflammatory, anti-oxidative and blood glucose-lowering properties. This review aims to summarise evidences for the cellular and molecular mechanism of Propolis in inflammation, oxidative stress, and glycemic control. Propolis stimulate the production and secretion of anti-inflammatory cytokines and to inhibit the production of inflammatory cytokines and due to its various antioxidant and poly-phenolic compounds may has a role in control and treating some of the chronic diseases. Most studies have shown that Propolis may affect metabolic factors including plasma insulin levels, and it has proposed that it could be used in the prevention and treatment of T2D Mellitus. In general, to demonstrate the definite effects of Propolis on chronic diseases, more studies are required using larger sample sizes and various doses of Propolis, using better characterized and standardized agents.

中文翻译：

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蜂胶对慢性疾病中炎症，氧化应激和血糖控制的影响的分子和细胞机制。

蜂胶是一种粘性的树脂材料，从植物中收集并与蜡和其他成分混合。据报道具有抗炎，抗氧化和降低血糖的特性。这篇综述旨在总结蜂胶在炎症，氧化应激和血糖控制中的细胞和分子机制。蜂胶刺激抗炎细胞因子的产生和分泌，并抑制炎性细胞因子的产生，并且蜂胶由于其各种抗氧化剂和多酚化合物可能在控制和治疗某些慢性疾病中起作用。大多数研究表明，蜂胶可能会影响包括血浆胰岛素水平在内的代谢因子，因此建议将其用于预防和治疗T2D糖尿病。一般来说，