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Study on the Therapeutic Efficacy of a Polyphitho Therapeutic Compound in Primary and Secondary Lymphedema
Lymphatic Research and Biology ( IF 1.4 ) Pub Date : 2021-02-24 , DOI: 10.1089/lrb.2019.0080
Sandro Michelini 1 , Vincenzo Gasbarro 2 , Marcello Izzo 2 , Francesco G Albergati 3
Affiliation  

The role of the interstitial matrix in regulating exchanges and interactions at the level of the microvascular units, between the corpuscular component and the vascular and nerve structures, has long been known. Equally known are the objective and subjective clinical manifestations that these pathologies trigger in the patient, both in primary and secondary forms: embarrassment, asthenia, alterations of exteroceptive and proprioceptive sensitivity, pain, reduced capacity, and functional autonomy, affecting both the lower and the upper limbs. The authors studied 136 patients with I and II clinical stage lymphedema according to the International Society of Lymphology stadiation. Patients were treated with Lymdiaral, 20 drops three times a day for 90 consecutive days. The following parameters were examined in basal conditions and after treatment: ultrasound measurement of suprafascial thickness, short form healthy survey version 12 (SF12), body mass index, and limb circumferences in specific points of reference. The results demonstrate the effectiveness of the therapeutic principle both in the reduction of limb circumferences and in the improvement of the parameters related to the quality of life expressed by the SF12 items. There were no substantial differences in the results between primary and secondary forms.

中文翻译:

多酚治疗化合物治疗原发性和继发性淋巴水肿的疗效研究

间质基质在微血管单位水平上调节交换和相互作用中的作用,在微粒成分与血管和神经结构之间,早已为人所知。同样已知的是这些病理在患者中引发的客观和主观临床表现,包括原发性和继发性:尴尬、虚弱、外感受和本体感受敏感性的改变、疼痛、能力下降和功能自主性,影响下肢和下肢。上肢。根据国际淋巴学会 stadation,作者研究了 136 名 I 和 II 期临床淋巴水肿患者。患者接受 Lymdiaral 治疗,连续 90 天,每天 3 次,每次 20 滴。在基础条件下和治疗后检查以下参数:筋膜上厚度的超声测量、简短形式的健康调查第 12 版 (SF12)、体重指数和特定参考点的四肢周长。结果证明了治疗原理在减少肢体周长和改善与 SF12 项目表达的生活质量相关的参数方面的有效性。初级和次级形式之间的结果没有实质性差异。
更新日期:2021-02-25
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