Abstract

Purpose

Our purpose is to assess the efficacy and safety of percutaneous US-guided microwave ablation (MWA) for cervical metastatic lymph nodes from papillary thyroid carcinomas (PTC).

Methods

In total, 37 patients with 98 cervical metastatic lymph nodes from PTC were enrolled in this retrospective study. Among them, 8 had subtotal thyroidectomy, 4 lobectomy, 2 no operation, and the rest total thyroidectomy. A multipoint and multiplane fixed ablation method was used. Monitoring of ablation process and clinical follow-up consisted of US or CEUS.

Results

All 98 metastatic lymph nodes successfully treated in a single session with 100% complete ablation. The average longest and shortest diameter of the tumors were reduced from 13.21 ± 5.86 mm to 6.74 ± 5.66 mm (p =.00) and from 9.29 ± 4.09 mm to 4.31 ± 3.56 mm (p =.00) at the final follow-up. There were no evidence of recurrence at ablated sites. The common intraoperative complications were a burning sensation and pain. Only 3 patients had vagal reflex.

Conclusions

US-guided MWA can effectively control cervical metastatic lymph nodes from PTC. MWA may become an alternative therapy in selected PTC patients with cervical lymph node metastasis.

中文翻译：

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经皮超声引导微波消融治疗甲状腺乳头状癌宫颈转移淋巴结的疗效和安全性。

摘要

目的

我们的目的是评估经皮超声引导的微波消融（MWA）对甲状腺乳头状癌（PTC）的宫颈转移性淋巴结的疗效和安全性。

方法

这项回顾性研究总共纳入了37例PTC的98例宫颈转移性淋巴结的患者。其中，甲状腺大部切除术8例，肺叶切除术4例，无手术2例，其余全甲状腺切除术。使用了多点多平面固定消融方法。消融过程和临床随访的监测由US或CEUS组成。

结果

所有98个转移淋巴结均在100％完全消融的情况下成功治疗。 在最后一次随访中，平均最长和最短肿瘤直径从13.21±5.86 mm减小到6.74±5.66 mm（p  = .00），从9.29±4.09 mm减小到4.31±3.56 mm（p = .00） 。没有证据显示消融部位复发。常见的术中并发症为烧灼感和疼痛。只有3例患者出现迷走神经反射。

结论

美国指导的MWA可有效控制PTC的宫颈转移淋巴结。MWA可能会成为某些患有颈淋巴结转移的PTC患者的替代疗法。