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Selection for Divergent Reproductive Investment Affects Neuron Size and Foliation in the Cerebellum.
Brain, Behavior and Evolution ( IF 1.7 ) Pub Date : 2020-08-12 , DOI: 10.1159/000509068
Ryaan El-Andari 1 , Felipe Cunha 1 , Barbara Tschirren 2 , Andrew N Iwaniuk 3
Affiliation  

The cerebellum has a highly conserved internal circuitry, but varies greatly in size and morphology within and across species. Despite this variation, the underlying volumetric changes among the layers of the cerebellar cortex or their association with Purkinje cell numbers and sizes is poorly understood. Here, we examine intraspecific scaling relationships and variation in the quantitative neuroanatomy of the cerebellum in Japanese quail (Coturnix japonica) selected for high or low reproductive investment. As predicted by the circuitry of the cerebellum, the volumes of the constituent layers of the cerebellar cortex were strongly and positively correlated with one another and with total cerebellar volume. The number of Purkinje cells also significantly and positively co-varied with total cerebellar volume and the molecular layer, but not the granule cell layer or white matter volumes. Purkinje cell size and cerebellar foliation did not significantly covary with any cerebellar measures, but differed significantly between the selection lines. Males and females from the high-investment lines had smaller Purkinje cells than males and females from the low-investment lines and males from the high-investment lines had less folded cerebella than quail from the low-investment lines. These results suggest that within species, the layers of the cerebellum increase in a coordinated fashion, but Purkinje cell size and cerebellar foliation do not increase proportionally with overall cerebellum size. In contrast, selection for differential reproductive investment affects Purkinje cell size and cerebellar foliation, but not other quantitative measures of cerebellar anatomy.
Brain Behav Evol


中文翻译:

选择不同的生殖投资会影响小脑中的神经元大小和叶子。

小脑具有高度保守的内部电路,但在物种内部和物种之间的大小和形态上差异很大。尽管有这种变化,但对小脑皮层各层之间潜在的体积变化或其与浦肯野细胞数量和大小的关联知之甚少。在这里,我们检查了日本鹌鹑(Coturnix japonica )小脑定量神经解剖学的种内缩放关系和变化) 选择高或低的生殖投资。正如小脑回路所预测的那样,小脑皮层构成层的体积彼此之间以及与小脑总体积呈强正相关。浦肯野细胞的数量也与总小脑体积和分子层显着且正相关,但与颗粒细胞层或白质体积无关。浦肯野细胞大小和小脑叶理与任何小脑测量没有显着共变,但在选择线之间存在显着差异。高投资品系的雄性和雌性的浦肯野细胞比低投资品系的雄性和雌性小,高投资品系的雄性小脑折叠比低投资品系的鹌鹑少。这些结果表明,在物种内,小脑的层数以协调的方式增加,但浦肯野细胞大小和小脑叶理不随小脑整体大小成比例增加。相比之下,差异生殖投资的选择会影响浦肯野细胞大小和小脑叶理,但不会影响小脑解剖结构的其他定量测量。
大脑行为进化
更新日期:2020-08-12
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