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Location, Location, Location: Transcriptional Control of Astrocyte Heterogeneity.
Trends in Immunology ( IF 16.8 ) Pub Date : 2020-08-12 , DOI: 10.1016/j.it.2020.07.011 Marci F Rosenberg 1 , Anna V Molofsky 1
中文翻译:
位置,位置,位置:星形胶质细胞异质性的转录控制。
更新日期:2020-08-27
Trends in Immunology ( IF 16.8 ) Pub Date : 2020-08-12 , DOI: 10.1016/j.it.2020.07.011 Marci F Rosenberg 1 , Anna V Molofsky 1
Affiliation
Huang et al. have found that deletion of astrocyte lineage-specifying transcription factor NFIA from mature astrocytes alters astrocyte morphology, molecular identity, and synaptic-support capacity in a region-specific manner. We discuss the implications of these findings in light of emerging roles for astrocytes in immune cell crosstalk.
中文翻译:
位置,位置,位置:星形胶质细胞异质性的转录控制。
黄等人。已经发现从成熟星形胶质细胞中删除星形胶质细胞谱系特异性转录因子 NFIA 会以区域特异性方式改变星形胶质细胞形态、分子特性和突触支持能力。我们根据星形胶质细胞在免疫细胞串扰中的新作用来讨论这些发现的意义。